Nosocomial Jejunal Mucormycosis - an Unusual Cause of Perforation Peritonitis

نویسندگان

  • Chandan Kumar Dept. of Pathology, University College of Medical Sciences, University of Delhi, Delhi, India
  • Neelam Wadhwa Dept. of Pathology, University College of Medical Sciences, University of Delhi, Delhi, India
  • Nirupma Khan Dept. of Pathology, Guru Teg Bahadur Hospital, Shahdra, Delhi, India
  • Pragya Jain Dept. of Pathology, University College of Medical Sciences, University of Delhi, Delhi, India
  • Preeti Diwaker Dept. of Pathology, University College of Medical Sciences, University of Delhi, Delhi, India
چکیده مقاله:

Mucormycosis is a rare but highly invasive opportunistic fungal infection. Gastrointestinal disease although uncommon is highly fatal. We report a case of jejunal mucormycosis in a 24 year old undernourished female with preceding surgical intervention for acute intestinal obstruction of tubercular etiology. On 8th post-operative day, she developed oozing from suture line, prompting exploratory laparotomy, bowel resection, jejunostomy and ileal mucus fistula. Resected bowel showed one perforation and several areas of impending perforations. Characteristic broad, pauci-septate hyaline, empty looking hyphae with infrequent branching were found transmurally and showing angio-invasion. Local intestinal tissue trauma coupled with her sub-normal immune status permitted this unusual nosocomial infection. Histopathologic demonstration of the fungus in surgical specimens remains cornerstone of diagnosis of mucormycosis in view of its non-specific symptoms, low isolation rates of mycologic culture and lack of other rapid tests. 

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عنوان ژورنال

دوره 12  شماره 3

صفحات  295- 300

تاریخ انتشار 2017-07-01

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